Pernicious anaemia in Sudanese patients.

Pernicious anaemia in Sudanese patients.
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苏丹患者的恶性贫血。

DOI:
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发表时间:
1978
影响因子:
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通讯作者:
M. Ahmed
M. Ahmed
中科院分区:
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文献类型:
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作者:
A. Abu;M. Ahmed

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尽管恶性贫血在高加索人种中很常见,但在其他人种中只报告了罕见的病例。最近在苏丹发现的三例病例表明,这种疾病在其他种族中可能并不像之前认为的那样罕见。在研究的三名患者中,三人都表现出各种可能与恶性贫血有关的身体症状。实验室检查包括血常规、骨髓抽吸、血清维生素B12和叶酸测定、席林试验、胃酸分泌测定和其他检查均证实所有病例均为恶性贫血。确诊后,患者接受维生素B12注射治疗,均取得良好效果。由于该病的症状各不相同,彻底的实验室检测对于准确的诊断是必不可少的。随着非洲欠发达地区设施的改善,将有可能更准确地诊断这种疾病。因此,毫无疑问,在其他种族中会发现更多的恶性贫血病例。
Although pernicious anaemia occurs commonly among the Caucasian race only rare cases have been reported among other races. Three cases recently identified in the Sudan indicate that the disease may not be as rare among other races as previously believed. Of the three patients studied all three exhibited a variety of physical symptoms that can be associated with pernicious anaemia. Laboratory tests including routine blood counts bone marrow aspiration serum Vitamin B12 and folate evaluation the Schilling test gastric acid secretion estimates and other tests confirmed the diagnosis of pernicious anaemia in all cases. Following diagnosis the patients were given Vitamin B12 injection therapy and they all responded favorably. Because the symptoms for the disease vary thorough laboratory testing is essential for accurate diagnosis. With the improvement of facilities in the less developed areas of Africa it will be possible to diagnose the disease more precisely. As a result undoubtedly more cases of pernicious anaemia will be found among other races.