Efficient construction of five-membered aromatic and nonaromatic heterocycles from 1,6-enynes by a palladium-catalyzed domino coupling/cycloisomerization process.
Efficient construction of five-membered aromatic and nonaromatic heterocycles from 1,6-enynes by a palladium-catalyzed domino coupling/cycloisomerization process.
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DOI：
10.1021/jo9020776
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发表时间：
2010-02
期刊：
影响因子：
--
通讯作者：
Tuan-jie Meng;Yimin Hu;Shaowu Wang
中科院分区：
文献类型：
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作者：
Tuan-jie Meng;Yimin Hu;Shaowu Wang
钯催化的1，6-烯炔和卤代芳烃的偶联/环化异构化反应是合成五元芳杂环和非芳杂环的有效方法。结果表明，炔末端的取代基对产物的选择性生成有显著影响。
General and efficient methods for the construction of five-membered aromatic and nonaromatic heterocycles by palladium-catalyzed coupling/cycloisomerization of 1,6-enynes and aryl halides have been developed. Results indicate that substituents at the terminus of the alkynes have a significant effect on the selective formation of the products.