Cyanuric chloride-imidazole dendrimer functionalized nanoparticles as an adsorbent for magnetic solid phase extraction of quaternary ammonium compounds from fruit and vegetable puree based infant foods
Cyanuric chloride-imidazole dendrimer functionalized nanoparticles as an adsorbent for magnetic solid phase extraction of quaternary ammonium compounds from fruit and vegetable puree based infant foods
复制标题
氰尿酰氯-咪唑树枝状聚合物功能化纳米颗粒作为磁性固相萃取果蔬泥婴儿食品中季铵化合物的吸附剂
DOI：
10.1016/j.chroma.2020.461735
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发表时间：
2021
影响因子：
4.1
通讯作者：
Xu Xiangdong
中科院分区：
文献类型：
--
作者：
Zhao Tangjuan;Zhang Mengyan;Ma Ling;Ma Li;Shi Hongmei;Kang Weijun;Xu Xiangdong
制备了一种新型磁性固相萃取材料（Fe3O4@SiO2-NH 2-G2），并将其用于婴幼儿果蔬产品中7种季铵盐类化合物的吸附和高效液相色谱-串联质谱（HPLC-MS/MS）分析。本文以Fe3O4@SiO2-NH 2为原料，以三聚氯氰和咪唑组成的树枝状大分子（G2）为模板，合成了Fe3O4@SiO2-NH 2-G2。采用透射电子显微镜（TEM）、傅里叶变换红外光谱（FT-IR）、X射线衍射（XRD）和振动样品磁强计（VSM）对磁性材料的形貌、结构和磁性能进行了表征。对影响萃取效率的吸附剂用量、样品pH值、萃取时间、洗脱剂种类和解吸时间等关键参数进行了优化。该方法线性良好，相关系数（R2）为0.9992-0.9999，检测下限（LOD）为0.05-0.50 μg kg−1，定量限（LOQ）为0.20-2.00 μg kg−1。3种婴幼儿果蔬产品的加标回收率在80.12%~ 101.35%之间，相对标准偏差（RSD）小于12.04%。该方法是一种有效的样品前处理方法，在复杂基体中QAC分析中具有良好的前景。
A novel magnetic solid-phase extraction (MSPE) material (Fe3O4@SiO2-NH2-G2) had been prepared and employed for adsorption and analysis of seven quaternary ammonium compounds (QACs) in infant fruit and vegetable products coupled with high performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS). In this paper, Fe3O4@SiO2-NH2-G2 was synthesized based on Fe3O4@SiO2-NH2and dendrimer (G2) consisting of cyanuric chloride and imidazole. The morphology, configuration and magnetic behavior of the magnetic material were characterized by transmission electron microscopy (TEM), Fourier transform infrared spectrometry (FT-IR), X-ray diffraction (XRD), and vibrating sample magnetometer (VSM). Critical parameters affecting extraction efficiency, such as the adsorbent amount, sample pH, extraction time, the type of eluent, and desorption time, were optimized. The proposed method provided good linearity with the correlation coefficients (R2) of 0.9992-0.9999, low limits of detection (LODs) (0.05-0.50 μg kg−1) and limits of quantitation (LOQs) (0.20-2.00 μg kg−1). The satisfactory method recoveries in three spiked infant fruit and vegetable products samples were between 80.12% and 101.35% with the relative standard deviations (RSDs) less than 12.04%. In summary, the established method was an effective sample preparation method and showed good prospect for the analysis of QACs in complex matrices.