Role of non-conventional T lymphocytes in respiratory infections: the case of the pneumococcus.
Role of non-conventional T lymphocytes in respiratory infections: the case of the pneumococcus.
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DOI:
10.1371/journal.ppat.1004300
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发表时间:
2014-10
期刊:
影响因子:
6.7
通讯作者:
Trottein F
中科院分区:
文献类型:
--
作者:
Ivanov S;Paget C;Trottein F
Non-conventional T lymphocytes constitute a special arm of the immune system and act as sentinels against pathogens at mucosal surfaces. These non-conventional T cells (including mucosal-associated invariant T [MAIT] cells, gamma delta [γδ] T cells, and natural killer T [NKT] cells) display several innate cell-like features and are rapidly activated by the recognition of conserved, stress-induced, self, and microbial ligands. Here, we review the role of non-conventional T cells during respiratory infections, with a particular focus on the encapsulated extracellular pathogen Streptococcus pneumoniae, the leading cause of bacterial pneumonia worldwide. We consider whether MAIT cells, γδ T cells, and NKT cells might offer opportunities for preventing and/or treating human pneumococcus infections.
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影响因子:
11.1
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Yin, Yibing
影响因子:
4.4
作者:
Bilenki, L;Wang, SH;Yang, X
通讯作者:
Yang, X
影响因子:
4.4
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Devilder, MC;Maillet, S;Scotet, E
通讯作者:
Scotet, E
影响因子:
8.4
作者:
Deng S;Bai L;Reboulet R;Matthew R;Engler DA;Teyton L;Bendelac A;Savage PB
通讯作者:
Savage PB
DOI:
10.1073/pnas.152298499
发表时间:
2002-07-23
影响因子:
11.1
作者:
Beres, SB;Sylva, GL;Musser, JM
通讯作者:
Musser, JM