Fast comprehensive single-sequence four-dimensional pediatric knee MRI with T(2) shuffling.
Fast comprehensive single-sequence four-dimensional pediatric knee MRI with T(2) shuffling.
复制标题
DOI：
10.1002/jmri.25508
复制
发表时间：
2017-06
期刊：
影响因子：
--
通讯作者：
Vasanawala SS
中科院分区：
文献类型：
--
作者：
Bao S;Tamir JI;Young JL;Tariq U;Uecker M;Lai P;Chen W;Lustig M;Vasanawala SS
旨在开发和临床评价基于体积快速自旋回波（3DFSE）的儿科膝关节磁共振成像（MRI）技术，并将其诊断性能、图像质量和成像时间与传统2D方案进行比较。修改3DFSE序列，并将其与基于压缩传感的重建相结合，以解决多个图像对比度，这种技术称为T2洗牌（T2 Sh）。经机构审查委员会（IRB）批准，28名连续儿童被转诊接受3 T膝关节MRI，前瞻性接受标准临床膝关节方案，随后接受T2 Sh。T2 Sh性能由两名对诊断报告不知情的阅片人进行评估。通过病历图表审查和阅片人与骨科医生之间的共识解决解释差异。图像质量通过对解剖轮廓进行评级来评价，置信区间为95%。Wilcoxon秩和检验评估了零假设，即与传统2D相比，T2 Sh结构描绘没有变化。组内相关系数计算观察者之间的协议。比较常规方案与T2 Sh的成像时间。对于每位阅片者，T2 Sh报告和诊断报告之间的一致性分别为81%和87%。在共识审查后，与临床报告相比，T2 Sh检测临床相关结果的灵敏度为93%，特异性为100%。诊断或更好评级的95%置信区间为95- 100%，观察者间一致性为34-80%。T2 Sh与2D在结构勾画上无显著差异，但支持带除外（P < 0.05），2D更适合于T2 Sh。T2 Sh和常规检查的典型成像时间分别为7分钟和13分钟。使用T2 Sh进行单序列儿科膝关节检查是可行的，可提供多平面、可重新格式化的4D图像。
To develop and clinically evaluate a pediatric knee magnetic resonance imaging (MRI) technique based on volumetric fast spin-echo (3DFSE) and compare its diagnostic performance, image quality, and imaging time to that of a conventional 2D protocol. A 3DFSE sequence was modified and combined with a compressed sensing-based reconstruction resolving multiple image contrasts, a technique termed T2 Shuffling (T2Sh). With Institutional Review Board (IRB) approval, 28 consecutive children referred for 3T knee MRI prospectively underwent a standard clinical knee protocol followed by T2Sh. T2Sh performance was assessed by two readers blinded to diagnostic reports. Interpretive discrepancies were resolved by medical record chart review and consensus between the readers and an orthopedic surgeon. Image quality was evaluated by rating anatomic delineation, with 95% confidence interval. A Wilcoxon rank-sum test assessed the null hypothesis that T2Sh structure delineation compared to conventional 2D is unchanged. Intraclass correlation coefficients were calculated for interobserver agreement. Imaging time of the conventional protocol and T2Sh was compared. There was 81% and 87% concordance between T2Sh reports and diagnostic reports, respectively, for each reader. Upon consensus review, T2Sh had 93% sensitivity and 100% specificity compared to clinical reports for detection of clinically relevant findings. The 95% confidence interval of diagnostic or better rating was 95–100%, with 34–80% interobserver agreement. There was no significant difference in structure delineation between T2Sh and 2D, except for the retinaculum (P < 0.05), where 2D was preferred. Typical imaging time for T2Sh and the conventional exam was 7 and 13 minutes, respectively. A single-sequence pediatric knee exam is feasible with T2Sh, providing multiplanar, reformattable 4D images.
登录
查看更多内容
影响因子：
3.3
作者：
Uecker, Martin;Lai, Peng;Murphy, Mark J.;Virtue, Patrick;Elad, Michael;Pauly, John M.;Vasanawala, Shreyas S.;Lustig, Michael
通讯作者：
Lustig, Michael
影响因子：
3.3
作者：
Busse, Reed F.;Brau, Anja C. S.;Vu, Anthony;Michelich, Charles R.;Bayram, Ersin;Kijowski, Richard;Reeder, Scott B.;Rowley, Howard A.
通讯作者：
Rowley, Howard A.
影响因子：
3.3
作者：
Huang, Chuan;Graff, Christian G.;Clarkson, Eric W.;Bilgin, Ali;Altbach, Maria I.
通讯作者：
Altbach, Maria I.
膝关节 CUBE MRI 序列与传统 MRI 的诊断性能比较
影响因子：
2.6
作者：
Ai, T.;Zhang, W.;Li, X.
通讯作者：
Li, X.
影响因子：
1.7
作者：
Schub, David L.;Altahawi, Faysal;Saluan, Paul M.
通讯作者：
Saluan, Paul M.