Mathematical Analysis of a Kinetic Model for Cell Movement in Network Tissues
Mathematical Analysis of a Kinetic Model for Cell Movement in Network Tissues
复制标题
网络组织中细胞运动动力学模型的数学分析
DOI:
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发表时间:
2008
期刊:
影响因子:
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通讯作者:
Zhian Wang
中科院分区:
文献类型:
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作者:
T. Hillen;P. Hinow;Zhian Wang
Mesenchymal motion describes the movement of cells in biological tissues formed
by fibre networks. An important example is the migration of tumour cells through
collagen networks during the process of metastasis formation. We investigate the
mesenchymal motion model proposed by T. Hillen in [14] in higher
dimensions. We formulate the problem as an evolution equation in a Banach space
of measure-valued functions and use methods from semigroup theory to show the
global existence of mild and classical solutions. We investigate steady states of the
model and show that patterns of network type exist as steady states. For the
case of constant fibre distribution, we find an explicit solution and we prove
the convergence to the parabolic limit.