Depression is linked to uncontrolled hypertension: a case-control study from Karachi, Pakistan
Depression is linked to uncontrolled hypertension: a case-control study from Karachi, Pakistan
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DOI：
10.3109/09638237.2014.924047
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发表时间：
2014-12-01
影响因子：
3.3
通讯作者：
Khan, Mohammad Ataullah
中科院分区：
文献类型：
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作者：
Almas, Aysha;Patel, Junaid;Khan, Mohammad Ataullah
背景：高血压是心血管疾病的重要危险因素，在有精神疾病的人群中可能更为常见。目的：在卡拉奇的两个三级护理中心确定未控制的高血压与抑郁和焦虑障碍的相关性。方法：在卡拉奇的两家医院进行病例对照研究。2例为未控制高血压患者，对照组为控制高血压患者。以医院焦虑和抑郁量表(HADS)测量的焦虑或抑郁史为暴露。结果：共调查700名受试者，其中590人符合纳入标准并同意参加，323人(54.7%)被纳入为病例，267人(45.3%)为对照。平均年龄54.98岁(12.38岁)，男性229例(38%)。高血压失控和抑郁(HADS-D>；8)的优势比(OR)(95%CI)为2.02(1.44~2.83)，p
Background: High blood pressure is an important risk factor for cardiovascular disease and may be more prevalent in persons with psychopathology.Objective: To determine the association between uncontrolled hypertension with depressive and anxiety disorders in two tertiary care centers in Karachi.Methods: It was a case-control study conducted in two hospitals in Karachi. Cases were patients with uncontrolled hypertension and controls were patients with controlled hypertension. History of anxiety or depression as measured by Hospital Anxiety and Depression Scale (HADS) was the exposure. HADS of >8 was suggestive of having anxiety or depression.Results: A total of 700 participants were approached, out of whom 590 fulfilled the inclusion criteria and consented to participate, 323 (54.7%) participants were enrolled as cases and 267 (45.3%) as controls. Mean (SD) age was 54.98 (12.38) years, 229 (38%) were males. Odds ratio (OR) (95% CI) of having uncontrolled hypertension and being depressed (HADS-D>8) was 2.02 (1.44-2.83), p value