KRAS-related noncoding RNAs in pancreatic ductal adenocarcinoma
KRAS-related noncoding RNAs in pancreatic ductal adenocarcinoma
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DOI：
10.1016/j.cdtm.2016.11.012
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发表时间：
2016
影响因子：
--
通讯作者：
Jie Chen
中科院分区：
文献类型：
--
作者：
Shuang-Ni Yu;Yi-Hui Ma;Wu-Gan Zhao;Xiang-Lan Jin;Hai-Yan Yang;Ping-Ping Liu;Jie Chen
Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with a poor overall prognosis. However, curative resection during.the early stages of the disease can greatly improve survival rates, highlighting the importance of early screening and detection..Studies of noncoding RNAs, primarily microRNAs (miRNAs) and long noncoding RNAs (lncRNAs), provide important insights.into strategies for the early detection of KRAS-driven PDAC. Here, we summarize our studies and review current reports on research.investigating KRAS-related miRNAs and lncRNAs, emphasizing their aberrant expression, mechanisms, carcinogenic effects, and.prognostic and predictive capacities in PDAC.
