An Optimal Sliding Choke Antenna for Hepatic Microwave Ablation
An Optimal Sliding Choke Antenna for Hepatic Microwave Ablation
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DOI：
10.1109/tbme.2009.2025264
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发表时间：
2009-10-01
影响因子：
4.6
通讯作者：
Mahvi, David M.
中科院分区：
文献类型：
--
作者：
Prakash, Punit;Converse, Mark C.;Mahvi, David M.
微波消融（MWA）是一种微创技术，越来越多地用于肝脏肿瘤的热治疗。有效的MWA需要有效的间质天线，在原位破坏肿瘤和健康组织的边缘，同时最大限度地减少对器官其余部分的损害。在此之前，我们提出了一种将天线有限元模型与实数编码多目标遗传算法相结合的MWA天线优化设计方法。我们利用这一过程优化了一种微创扼流圈天线的设计，该天线可以通过调整治疗时间和天线的滑动结构来创建可调节大小（半径1-2厘米）的近球形消融区。计算结果在离体牛肝脏实验中得到了验证。优化过程产生的天线反射系数低于-30 dB，能够在2.45 GHz下使用100 W输入功率，处理时间小于2分钟的情况下产生半径为2 cm的球形烧蚀区。
Microwave ablation (MWA) is a minimally invasive technique increasingly used for thermal therapy of liver tumors. Effective MWA requires efficient interstitial antennas that destroy tumors and a margin of healthy tissue, in situ, while minimizing damage to the rest of the organ. Previously, we presented a method for optimizing MWA antenna designs by coupling finite element method models of antennas with a real-coded, multiobjective genetic algorithm. We utilized this procedure to optimize the design of a minimally invasive choke antenna that can be used to create near-spherical ablation zones of adjustable size (radius 1-2 cm) by adjusting treatment durations and a sliding structure of the antenna. Computational results were validated with experiments in ex vivo bovine liver. The optimization procedure yielded antennas with reflection coefficients below -30 dB, which were capable of creating spherical ablation zones up to 2 cm in radius using 100 W input power at 2.45 GHz with treatment durations under 2 min.