Chronic fatigue syndrome and other fatiguing illnesses in adolescents: A population-based study
Chronic fatigue syndrome and other fatiguing illnesses in adolescents: A population-based study
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DOI：
10.1016/s1054-139x(03)00372-0
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发表时间：
2004-07-01
影响因子：
7.6
通讯作者：
Reeves, WC
中科院分区：
文献类型：
--
作者：
Jones, JF;Nisenbaum, R;Reeves, WC
目的：了解12~17岁青少年慢性疲劳综合征(CFS)的患病率，描述其他疲劳性疾病的特点。成年人识别家庭中疲惫的青少年，并回答与儿童健康有关的问题。选定的青少年被邀请与父母/监护人一起到诊所就诊。经过临床评估后，他们被归类为CFS或1994年CFS定义中定义的其他疲劳状态。每年的电话采访和临床评估都会监测受试者的疲劳状态。使用Kruskal-Wallis检验、Mantel-Haenszel检验和精确McNemar检验对数据进行分析。结果：调查涉及34,018户90,316名居民。在8586名青少年中，138人有大于或等于1个月的疲劳，大多数(107或78%)在3年随访期间的某个时间点有慢性疲劳(大于或等于6个月)。其中28人被排除诊断。31人被认为患有CFS样疾病，并被邀请进行临床评估。11人同意参加，没有人符合疾病控制中心的病例定义。CFS类疾病的基线加权患病率为每100,000人中有338人。父母和青少年对疾病的描述存在显著差异。结论：青少年的CFS患病率明显低于成人。对青少年CFS的评估必须同时考虑父母和患者对疲劳和其他可能解释症状复杂的疾病的感知。(C)青少年医学学会，2004年。
Purpose: To estimate the prevalence of chronic fatigue syndrome (CFS) and describe characteristics of other fatiguing illnesses in adolescents (aged 12 through 17 years).Methods: We conducted a random digit dialing survey of the residents of Wichita, Kansas. Adults identified fatigued adolescents in the household and answered questions relating to the child's health. Selected adolescents were invited to attend a clinic with a parent/ guardian. After clinical evaluation they were classified as CFS or another fatigue state as defined in the 1994 CFS definition. Annual telephone interviews and clinical evaluations monitored subjects' fatigue status. Data were analyzed using the Kruskal-Wallis test, the Mantel-Haenszel test, and the exact McNemar test.Results: The survey contacted 34,018 households with 90,316 residents. Of 8586 adolescents, 138 had fatigue for greater than or equal to1 month and most (107 or 78%) had chronic fatigue (greater than or equal to6 months) at some point during the 3-year follow-up. Twenty-eight had exclusionary diagnoses. Thirty-one were considered to have a CFS-like illness and were invited for clinical evaluation. Eleven agreed to participate and none met the CFS case definition. The baseline weighted prevalence of CFS-like illness was 338 per 100,000. Significant differences existed between parental and adolescents' descriptions of illness.Conclusions: The prevalence of CFS among adolescents was considerably lower than among adults. Evaluation of CFS in adolescents must consider both parent and patient perception of fatigue and other illnesses that might explain the symptom complex. (C) Society for Adolescent Medicine, 2004.