Multi-spanning membrane proteins: how accurate are the models?
Multi-spanning membrane proteins: how accurate are the models?
复制标题
多跨膜蛋白：模型的准确性如何？
DOI：
10.1016/0968-0004(88)90101-6
复制
发表时间：
1988
影响因子：
13.8
通讯作者：
Lodish,HF
中科院分区：
文献类型：
--
作者：
Lodish,HF
目前完整膜蛋白的模型是基于长度为22个或更多残基的α-螺旋，其长度足以跨越磷脂双层。对于含有许多这样的潜在α-螺旋的蛋白质，最小长度的假设是不正确的;我建议膜转运蛋白的结构的替代模型。
Current models of integral membrane proteins are based on α-helices 22 or more residues in length, long enough to span the phospholipid bilayer. For proteins that contain many such potential α-helices the assumption of a minimum length is incorrect; I suggest alternative models for the structure of membrane transport proteins.