Iodine-Promoted Rapid Construction of Carbamoylphosphonates from Phosphinecarboxamides
Iodine-Promoted Rapid Construction of Carbamoylphosphonates from Phosphinecarboxamides
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碘促进从膦甲酰胺快速构建氨基甲酰膦酸酯
DOI：
10.1002/adsc.201800303
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发表时间：
2018
影响因子：
5.4
通讯作者：
Quan Zheng-Jun
中科院分区：
文献类型：
--
作者：
Wu Yong-Hui;Wu Qiu-Li;Wang Wen-Peng;Wang Xi-Cun;Quan Zheng-Jun
A one‐step, I2‐promoted P−H phosphorylation and oxygenation of phosphinecarboxamides to give carbamoylphosphonates was achieved. This transformation exhibits exceptional substrate generality and functional group compatibility and affords good to excellent yields of the desired phosphonates. Notably, cyclic carbamoylphosphonates can be obtained from diols. The mechanism was investigated using IR,1H and31P NMR spectroscopy.
