Electronic cigarettes for smoking cessation: a randomised controlled trial
Electronic cigarettes for smoking cessation: a randomised controlled trial
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DOI：
10.1016/s0140-6736(13)61842-5
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发表时间：
2013-11-16
期刊：
影响因子：
168.9
通讯作者：
Walker, Natalie
中科院分区：
文献类型：
--
作者：
Bullen, Christopher;Howe, Colin;Walker, Natalie
背景电子烟（电子烟）可以释放尼古丁并减轻烟草戒断症状，许多吸烟者使用电子烟来帮助戒烟。我们调查了电子烟是否比尼古丁贴片更有效地帮助吸烟者戒烟。方法我们在2011年9月6日至2013年7月5日期间在新西兰奥克兰进行了这项实用的随机对照优效性试验。将想要戒烟的成年（≥ 18岁）吸烟者随机分组（采用计算机区组随机化，区组大小为9，按种族[毛利人;太平洋人;或非毛利人，非太平洋人]，性别[男性或女性]和尼古丁依赖水平[>5或> 10]分层）。
Background Electronic cigarettes (e-cigarettes) can deliver nicotine and mitigate tobacco withdrawal and are used by many smokers to assist quit attempts. We investigated whether e-cigarettes are more effective than nicotine patches at helping smokers to quit.Methods We did this pragmatic randomised-controlled superiority trial in Auckland, New Zealand, between Sept 6, 2011, and July 5, 2013. Adult (>= 18 years) smokers wanting to quit were randomised (with computerised block randomisation, block size nine, stratified by ethnicity [Maori; Pacific; or non-Maori, non-Pacific], sex [men or women], and level of nicotine dependence [>5 or