LncRNAWiki: harnessing community knowledge in collaborative curation of human long non-coding RNAs

LncRNAWiki: harnessing community knowledge in collaborative curation of human long non-coding RNAs
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LncRNAWiki:利用社区知识协作管理人类长非编码 RNA

DOI:
10.1093/nar/gku1167
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发表时间:
2015-01-28
影响因子:
14.9
通讯作者:
Zhang, Zhang
Zhang, Zhang
中科院分区:
生物学2区
文献类型:
--
作者:
Ma, Lina;Li, Ang;Zhang, Zhang

文献摘要

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Long non-coding RNAs (lncRNAs) perform a diversity of functions in numerous important biological processes and are implicated in many human diseases. In this report we present lncRNAWiki (http://lncrna.big.ac.cn), a wiki-based platform that is open-content and publicly editable and aimed at community-based curation and collection of information on human lncRNAs. Current related databases are dependent primarily on curation by experts, making it laborious to annotate the exponentially accumulated information on lncRNAs, which inevitably requires collective efforts in community-based curation of lncRNAs. Unlike existing databases, lncRNAWiki features comprehensive integration of information on human lncRNAs obtained from multiple different resources and allows not only existing lncRNAs to be edited, updated and curated by different users but also the addition of newly identified lncRNAs by any user. It harnesses community collective knowledge in collecting, editing and annotating human lncRNAs and rewards community-curated efforts by providing explicit authorship based on quantified contributions. LncRNAWiki relies on the underling knowledge of scientific community for collective and collaborative curation of human lncRNAs and thus has the potential to serve as an up-to-date and comprehensive knowledgebase for human lncRNAs.