Cs2CO3-promoted one-pot synthesis of alkynylphosphonates, -phosphinates, and -phosphine oxides.
Cs2CO3-promoted one-pot synthesis of alkynylphosphonates, -phosphinates, and -phosphine oxides.
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DOI：
10.1021/jo500312n
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发表时间：
2014-03
期刊：
影响因子：
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通讯作者：
Yulei Wang;Jiepeng Gan;L. Liu;Hang Yuan;Yuxing Gao;Yan Liu;Yufen Zhao
中科院分区：
文献类型：
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作者：
Yulei Wang;Jiepeng Gan;L. Liu;Hang Yuan;Yuxing Gao;Yan Liu;Yufen Zhao
在无金属条件下，以亚磷酸三烷基酯、二苯基亚膦酸乙酯或苯基亚膦酸二乙酯为原料，通过Cs2 CO 3促进1，1-二溴-1-烯烃的磷酸化或膦化反应，一锅法合成了一系列有价值的炔基膦酸酯、炔基次膦酸酯和炔基氧化膦，产率从高到高。
A novel and efficient Cs2CO3-promoted phosphorylation or phosphinylation of various 1,1-dibromo-1-alkenes with readily available trialkyl phosphites, ethyl diphenylphosphinite, or diethyl phenylphosphonite has been developed under metal-free conditions, providing a practical and powerful tool for one-pot synthesis of valuable alkynylphosphonates, -phosphinates, and -phosphine oxides in good to excellent yields.