Tumor capacitance: Electrical measurements of renal neoplasia
Tumor capacitance: Electrical measurements of renal neoplasia
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DOI：
10.1097/01.ju.0000129300.61874.17
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发表时间：
2004-08-01
影响因子：
6.6
通讯作者：
Kavoussi, LR
中科院分区：
文献类型：
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作者：
Inagaki, T;Bhayani, SB;Kavoussi, LR
目的：研究表明生物组织具有独特的电特性。我们使用能够测量新鲜手术切除组织离体模型中组织内电容的专用探针来评估肾肿瘤的电特性。材料和方法：使用电监测装置以 1 MHz 的频率测量手术切除后新鲜获得的 34 个离体肾脏标本的组织电容。立即测量切除的肿瘤以及周围正常实质和脂肪的组织电容。使用测量的电容数据计算每个组织中的介电常数。将这些数据进行比较并与病理结果相关联。结果：34个标本的最终病理结果显示28个肾细胞癌（RCC）、3个嗜酸细胞瘤和3个血管平滑肌脂肪瘤。在 RCC 患者中，肿瘤组织的介电常数比周围正常实质高 1.43 +/- 0.39 倍 (p
Purpose: Studies have demonstrated that biological tissues possess unique electrical properties. We evaluate the electrical properties of renal tumors using a specialized probe with the capability of measuring intra-tissue capacitance in an ex vivo model of fresh surgically excised tissue.Materials and Methods: An electrical monitoring device was used to measure tissue capacitance at a frequency of 1 MHz on 34 ex vivo kidney specimens freshly obtained after surgical excision. Tissue capacitance was promptly measured in the excised tumor as well as surrounding normal parenchyma and fat. Dielectric permittivity in each tissue was calculated using the measured capacitance data. These data were compared and correlated to pathological findings.Results: The final pathology on the 34 specimens revealed 28 renal cell carcinomas (RCC), 3 oncocytomas and 3 angiomyolipomas. In patients with RCC dielectric permittivity of tumor tissue was 1.43 +/- 0.39 times greater than that of surrounding normal parenchyma (p