Serum 25-Hydroxyvitamin D Concentrations Are Associated with Computed Tomography Markers of Subclinical Interstitial Lung Disease among Community-Dwelling Adults in the Multi-Ethnic Study of Atherosclerosis (MESA)
Serum 25-Hydroxyvitamin D Concentrations Are Associated with Computed Tomography Markers of Subclinical Interstitial Lung Disease among Community-Dwelling Adults in the Multi-Ethnic Study of Atherosclerosis (MESA)
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DOI：
10.1093/jn/nxy066
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发表时间：
2018-07-01
影响因子：
4.2
通讯作者：
Michos, Erin D.
中科院分区：
文献类型：
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作者：
Kim, Samuel M.;Zhao, Di;Michos, Erin D.
背景：活化维生素 D 具有抗炎特性。 25-羟基维生素 D [25(OH)D] 缺乏可能导致亚临床间质性肺病 (ILD)。 目的：我们研究了基线时无心血管疾病的中老年人血清 25(OH)D 浓度与亚临床 ILD 之间的关联。方法：我们研究了 6302 名基线血清 25(OH)D 浓度的多种族动脉粥样硬化研究 (MESA) 参与者和计算机断层扫描 (CT) 成像跨越
Background: Activated vitamin D has anti-inflammatory properties. 25-Hydroxyvitamin D [25(OH)D] deficiency might contribute to subclinical interstitial lung disease (ILD).Objective: We examined associations between serum 25(OH)D concentrations and subclinical ILD among middle-aged to older adults who were free of cardiovascular disease at baseline.Methods: We studied 6302 Multi-Ethnic Study of Atherosclerosis (MESA) participants who had baseline serum 25(OH)D concentrations and computed tomography (CT) imaging spanning