Helping behavior in prairie voles: A model of empathy and the importance of oxytocin.
Helping behavior in prairie voles: A model of empathy and the importance of oxytocin.
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DOI：
10.1016/j.isci.2022.103991
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发表时间：
2022-04-15
期刊：
影响因子：
5.8
通讯作者：
Sato N
中科院分区：
文献类型：
--
作者：
Kitano K;Yamagishi A;Horie K;Nishimori K;Sato N
几项研究表明，啮齿动物表现出同情反应和帮助他人的行为。我们研究了草原田鼠是否会帮助被水浸透的同种田鼠打开一扇通往安全区域的门。打开门的延迟时间随着任务的进行而减少。雌性和雄性田鼠以相同的比率靠近浸泡过的田鼠，并且以相似的延迟打开门。当不用水浸泡时，开门潜伏期不减小。这表明同种动物的痛苦是学习开门的必要条件，草原田鼠的开门行为与帮助行为相对应。此外，我们还研究了催产素受体基因缺失的草原田鼠的助人行为。催产素受体基因敲除的田鼠对开门行为的学习能力较弱，对浸泡过的同种生物的兴趣也较低。这表明催产素对帮助行为的出现很重要。草原田鼠对处于困境的同伴表现出了帮助行为，而帮助行为的性别对同伴的帮助行为没有影响，当同伴没有处于困境时，催产素受体敲除的草原田鼠表现出了更少的帮助行为；啮齿动物的行为
Several studies suggest that rodents show empathic responses and helping behavior toward others. We examined whether prairie voles would help conspecifics who were soaked in water by opening a door to a safe area. Door-opening latency decreased as task sessions progressed. Female and male voles stayed close to the soaked voles' side at equal rates and opened the door with similar latencies. When the conspecific was not soaked in water, the door-opening latency did not decrease. This suggests that the distress of the conspecific is necessary for learning to open the door and that the door-opening performed by prairie voles corresponds to helping behavior. Additionally, we examined the helping behavior in prairie voles in which oxytocin receptors were genetically knocked out. Oxytocin receptor knockout voles demonstrated less learning of the door-opening behavior and less interest in soaked conspecifics. This suggests that oxytocin is important for the emergence of helping behavior. Prairie voles demonstrated helping behavior toward a cagemate in distress There was no difference in helping behavior depending on the helper’s sex Learning of the helping behavior was prevented when cagemates were not in distress Oxytocin receptor knockout prairie voles demonstrated less helping behavior Evolutionary biology; rodent behavior
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影响因子：
8.2
作者：
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通讯作者：
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作者：
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