Three-dimensional imaging of absolute blood flow velocity and blood vessel position under low blood flow velocity based on Doppler signal information included in scattered light from red blood cells
Three-dimensional imaging of absolute blood flow velocity and blood vessel position under low blood flow velocity based on Doppler signal information included in scattered light from red blood cells
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DOI：
10.1063/1.4994080
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发表时间：
2017-11
影响因子：
3.2
通讯作者：
T. Kyoden;S. Akiguchi;Tomoki Tajiri;T. Andoh;T. Hachiga
中科院分区：
文献类型：
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作者：
T. Kyoden;S. Akiguchi;Tomoki Tajiri;T. Andoh;T. Hachiga
开发糖尿病患者闭塞远端血管的体内可视化系统是我们研究的主要目标。我们在此描述了两束多点激光多普勒测速仪（MLDV），它测量瞬时多点流速，可用于观察外周血管中的血流速度。通过使用电动平台在测量速度的同时水平和深度方向移动测量点，可以利用三维空间中的血流速度来观察皮肤中血管的路径。显示血管与周围组织之间信号功率密度的关系，帮助我们识别血管的位置。双光束MLDV可用于同时确定绝对血流速度分布并识别皮肤中的血管位置。
The development of a system for in vivo visualization of occluded distal blood vessels for diabetic patients is the main target of our research. We herein describe two-beam multipoint laser Doppler velocimetry (MLDV), which measures the instantaneous multipoint flow velocity and can be used to observe the blood flow velocity in peripheral blood vessels. By including a motorized stage to shift the measurement points horizontally and in the depth direction while measuring the velocity, the path of the blood vessel in the skin could be observed using blood flow velocity in three-dimensional space. The relationship of the signal power density between the blood vessel and the surrounding tissues was shown and helped us identify the position of the blood vessel. Two-beam MLDV can be used to simultaneously determine the absolute blood flow velocity distribution and identify the blood vessel position in skin.