Extending CD spectra of proteins to 168 nm improves the analysis for secondary structures.

Extending CD spectra of proteins to 168 nm improves the analysis for secondary structures.
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DOI:
10.1016/0003-2697(92)90473-k
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发表时间:
1992-02
影响因子:
2.9
通讯作者:
Arazdordi Toumadje;Stewart W. Alcorn;W. Johnson
Arazdordi Toumadje;Stewart W. Alcorn;W. Johnson
中科院分区:
生物学4区
文献类型:
--
作者:
Arazdordi Toumadje;Stewart W. Alcorn;W. Johnson

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The CD spectra for 10 proteins with known secondary structure have been extended from 178 to 168 nm. Combined with the data for 6 other proteins investigated previously, this produces a basis set of 16 proteins, which can be used to analyze CD spectra for secondary structure. Extending the spectra adds another CD band to the data and increases the information content from the equivalent of five to six. Analyzing the CD for each of the 16 proteins in the basis set with the 15 other proteins shows a modest improvement in the prediction of secondary structure with the extended CD spectra.