Recent developments in trace analysis of poly- and perfluoroalkyl substances
Recent developments in trace analysis of poly- and perfluoroalkyl substances
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DOI：
10.1007/s00216-011-4823-8
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发表时间：
2011-06-01
影响因子：
4.3
通讯作者：
van Leeuwen, Stefan P. J.
中科院分区：
文献类型：
--
作者：
Berger, Urs;Kaiser, Mary A.;van Leeuwen, Stefan P. J.
重点介绍了环境和人体样品中全氟烷基物质和多氟烷基物质(PFASs)超痕量测定的最新进展、改进和趋势，并概述和讨论了剩余的挑战和不确定性。了解PFAS在表面的吸附、不同基质的影响、不同的PFAS异构体响应系数、采样、样品制备和分析的潜在偏差影响等因素的分析影响，对于在痕量水平上测量高氟化合物至关重要。这些错综复杂的分析问题以及忽视正确处理它们的潜在后果将被讨论，并用实例加以记录。对于越来越多的环境和人类关注的全氟辛烷磺酸，特定的异构体分析和强有力的多化学方法的开发被确定为方法开发的主要趋势。最后，根据实验室间比较研究的结果，讨论了当前分析方法准确度的现状。
Recent developments, improvements, and trends in the ultra-trace determination of per- and polyfluoroalkyl substances (PFASs) in environmental and human samples are highlighted and the remaining challenges and uncertainties are outlined and discussed. Understanding the analytical implications of such things as adsorption of PFASs to surfaces, effects of differing matrices, varying PFAS isomer response factors, potential bias effects of sampling, sample preparation, and analysis is critical to measuring highly fluorinated compounds at trace levels. These intricate analytical issues and the potential consequences of ignoring to deal with them correctly are discussed and documented with examples. Isomer-specific analysis and the development of robust multi-chemical methods are identified as topical trends in method development for an ever-increasing number of PFASs of environmental and human interest. Ultimately, the state-of-the-art of current analytical method accuracy is discussed on the basis of results from interlaboratory comparison studies.