Gene delivery of indoleamine 2,3‐dioxygenase prolongs cardiac allograft survival by shaping the types of T‐cell responses

Gene delivery of indoleamine 2,3‐dioxygenase prolongs cardiac allograft survival by shaping the types of T‐cell responses
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DOI:
10.1002/jgm.1201
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发表时间:
2008-07
期刊:
The Journal of Gene Medicine
影响因子:
--
通讯作者:
Guang Yu;H. Dai;Jie Chen;L. Duan;Min Gong;Li Liu;P. Xiong;Cong-Yi Wang;M. Fang;F. Gong-F.-G
Guang Yu;H. Dai;Jie Chen;L. Duan;Min Gong;Li Liu;P. Xiong;Cong-Yi Wang;M. Fang;F. Gong-F.-G
中科院分区:
其他
文献类型:
--
作者:
Guang Yu;H. Dai;Jie Chen;L. Duan;Min Gong;Li Liu;P. Xiong;Cong-Yi Wang;M. Fang;F. Gong-F.-G

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We investigated the hypothesis that overexpression of indoleamine 2,3‐dioxygenase (IDO) by a cardiac allograft may result in a survival advantage of the allograft by creating a tolerogenic microenvironment.