Increased and More Heterogeneous Gadoxetic Acid Uptake of the Liver Parenchyma after Hepatitis C Virus Eradication by Direct Antiviral Agent.
Increased and More Heterogeneous Gadoxetic Acid Uptake of the Liver Parenchyma after Hepatitis C Virus Eradication by Direct Antiviral Agent.
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DOI：
10.2463/mrms.tn.2019-0183
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发表时间：
2020-12-01
期刊：
影响因子：
--
通讯作者：
Honda H
中科院分区：
文献类型：
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作者：
Fujita N;Nishie A;Asayama Y;Ishigami K;Nakayama T;Ushijima Y;Kakihara D;Takayama Y;Morita K;Ishimatsu K;Takao S;Yoshizumi T;Furusyo N;Honda H
我们评价了直接抗病毒治疗(DAA)根除丙型肝炎病毒(丙型肝炎病毒)后肝实质摄取加多酸的变化。计算肝胆期肝脏与肌肉信号强度比的增加率、偏斜度和峰度。在持续的病毒学应答后，肝实质的加多西酸摄取增加，但变得不均匀。我们的研究证明，通过DAA治疗根除丙型肝炎病毒可以显著影响加多沙酸的摄取。
We evaluated the changes of gadoxetic acid uptake of the liver parenchyma after hepatitis C virus (HCV) eradication by direct-antiviral agent (DAA) therapy. The increase rate of the liver-to-muscle signal intensity ratio, the skewness and the kurtosis were calculated in the hepatobiliary phase. After sustained virological response, gadoxetic acid uptake of the liver parenchyma increased, but became heterogeneous. Our study proved that HCV eradication by DAA therapy could significantly affect gadoxetic acid uptake.