Treatment of reactive hypoglycemia with the macrobiotic Ma-pi 2 diet as assessed by continuous glucose monitoring: The MAHYP randomized crossover trial
Treatment of reactive hypoglycemia with the macrobiotic Ma-pi 2 diet as assessed by continuous glucose monitoring: The MAHYP randomized crossover trial
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DOI：
10.1016/j.metabol.2017.01.023
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发表时间：
2017-04-01
影响因子：
9.8
通讯作者：
Pozzilli, Paolo
中科院分区：
文献类型：
--
作者：
Soare, Andreea;Khazrai, Yeganeh Manon;Pozzilli, Paolo
背景和目标。建议采用营养疗法来治疗反应性低血糖 (RH)，这是一种以餐后四小时内发生低血糖为特征的疾病。长寿 Ma-Pi 2 饮食可改善 2 型糖尿病患者的血糖控制。我们探讨了这种饮食对患有 RH 的非糖尿病个体的结果的影响。材料和方法。在随机交叉设计中，12 名 RH 受试者被随机分为三天的 Ma-Pi 2 饮食和三天的对照饮食。受试者每三天中仅两天接受零食，并使用连续血糖监测进行监测。 24小时期间分为白天（08:00-22:30小时[细分为“白天不吃零食”和“白天有零食”]）和夜间（22:31-07:59小时）。两种饮食对 RH 事件（血糖
Background and Aims. Nutritional therapy is recommended for management of reactive hypoglycemia (RH), a condition characterized by hypoglycemia that occurs within four hours after a meal. The macrobiotic Ma-Pi 2 diet improves glycemic control in subjects with type 2 diabetes. We explored the effect of this diet on outcomes in non-diabetic individuals with RH.Materials and Methods. Twelve subjects with RH were randomized to the Ma-Pi 2 diet for three days and a control diet for three days in a randomized crossover design. Subjects received snacks on two days out of each three-day period only, and were monitored using continuous glucose monitoring. The 24-h period was divided into daytime (08:00-22:30 h [subdivided into 'daytime without snacks' and 'daytime with snacks']) and night-time (22:31-07:59 h). The effects of the two diets on the number of RH events (blood glucose