Geographic distribution of lymphatic filariasis in Haiti

Geographic distribution of lymphatic filariasis in Haiti
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DOI:
10.4269/ajtmh.2004.71.598
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发表时间:
2004-11-01
影响因子:
3.3
通讯作者:
Streit, TG
Streit, TG
中科院分区:
医学4区
文献类型:
--
作者:
De Rochars, MVEB;Milord, MD;Streit, TG

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虽然至少从18世纪中期以来,淋巴丝虫病就已在海地流行,但从未进行过全国性的丝虫病调查。作为消除丝虫病国家方案的第一步,我们于2001年1月至4月采用批量质量保证抽样方法,从全国所有133个乡的50-250名学龄儿童(6-11岁)中采集了血液。在22,365名接受检测的儿童中,901名(4.0%)为循环班氏丝虫抗原阳性。当按社区人口加权时,该年龄组的全国总抗原流行率为7.3%。在147个(87.9%)社区发现了受感染的儿童,受影响最严重的地区集中在该国的北方地区。只有16个社区(12.1%)的250名儿童全部抗原阴性。因此,W.在海地,班克罗夫特感染比以前认识到的要广泛得多;几乎全国人口都可能被认为有感染的危险。
Although lymphatic filariasis is known to have been endemic in Haiti since at least the mid 1700s, a national filariasis survey has never been conducted. As a first step in the national program to eliminate filariasis, we collected blood in January-April 2001 from 50-250 school children (6-11 years old) in all 133 communes of the country using an adaptation of the lot quality assurance sampling method. Of 22,365 children tested, 901 (4.0%) were positive for circulating Wuchereria bancrofti antigen. When weighted by commune population, the overall national antigen prevalence in this age group was 7.3%. Infected children were found in 147 (87.9%) communes, the most heavily affected areas being concentrated in the northern part of the country. In only 16 (12.1%) communes were all 250 children antigen negative. Thus, W. bancrofti infection in Haiti is much more widespread than previously realized; virtually the entire population of the country may be considered at risk of infection.