The control of peroxisome number and size during division and proliferation
The control of peroxisome number and size during division and proliferation
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DOI：
10.1016/j.ceb.2005.06.003
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发表时间：
2005-08-01
影响因子：
7.5
通讯作者：
Subramani, S
中科院分区：
文献类型：
--
作者：
Yan, MD;Rayapuram, N;Subramani, S
像其他亚细胞器一样，过氧化物酶体在细胞分裂期间分裂并分离为子细胞，但这种细胞器也可以响应环境线索而增殖或降解。尽管参与这些过程的机制和基因仍在积极研究中，但过氧化物酶体增殖中的重要参与者是动力蛋白相关蛋白（DRP），其通过DRP受体募集到细胞器膜。相关的DRPs也在线粒体和叶绿体的分裂中起作用。许多其他蛋白质和信号调节过氧化物酶体分裂和增殖，但它们的作用模式仍在研究中。
Like other subcellular organelles, peroxisomes divide and segregate to daughter cells during cell division, but this organelle can also proliferate or be degraded in response to environmental cues. Although the mechanisms and genes involved in these processes are still under active investigation, an important player in peroxisome proliferation is a dynamin-related protein (DRP) that is recruited to the organelle membrane by a DRP receptor. Related DRPs also function in the division of mitochondria and chloroplasts. Many other proteins and signals regulate peroxisome division and proliferation, but their modes of action are still being studied.