Usefulness of microalbuminuria versus the metabolic syndrome as a predictor of cardiovascular disease in women and men >40 years of age (from the Rancho Bernardo Study)
Usefulness of microalbuminuria versus the metabolic syndrome as a predictor of cardiovascular disease in women and men >40 years of age (from the Rancho Bernardo Study)
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DOI：
10.1016/j.amjcard.2007.12.030
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发表时间：
2008-05-01
影响因子：
2.8
通讯作者：
Barrett-Connor, Elizabeth
中科院分区：
文献类型：
--
作者：
Jassal, Simerjot Kaur;Langenberg, Claudia;Barrett-Connor, Elizabeth
为了研究代谢综合征和微量白蛋白尿对社区老年人心血管疾病（CVD）和冠心病（CHD）死亡率的性别特异性贡献，869名女性和575名男性，年龄为40至96岁（平均年龄71岁）1992年至1995年间完成了问卷调查、体格检查和空腹实验室检查。参与者平均随访8年。采用考克斯比例风险模型分析CVD和CHD死亡率。在基线时，267名参与者患有成人治疗组III代谢综合征，151名患有微量白蛋白尿，34名两者兼而有之。在随访期间，有180例CVD死亡，包括83例CHD死亡。在女性中，微量白蛋白尿与心血管疾病和冠心病死亡率的两倍增加相关（p
To examine the sex-specific contributions of the metabolic syndrome and microalbuminuria to cardiovascular disease (CVD) and coronary heart disease (CHD) mortality in community-dwelling older adults, 869 women and 575 men aged 40 to 96 years (mean age 71) completed questionnaires, physical examinations, and fasting laboratory tests between 1992 and 1995. Participants were followed over an average of 8 years. CVD and CHD mortality were analyzed using Cox proportional hazards models. At baseline, 267 participants had the Adult Treatment Panel III metabolic syndrome, 151 had microalbuminuria, and 34 had both. During follow-up, there were 180 CVD deaths, including 83 CHD deaths. In women, microalbuminuria was associated with a twofold increased risk of CVD and CHD mortality (p