Hydrodynamic radius of circular DNA is larger than that of linear DNA
Hydrodynamic radius of circular DNA is larger than that of linear DNA
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DOI：
10.1016/j.cplett.2005.10.115
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发表时间：
2006-01-25
影响因子：
2.8
通讯作者：
Yoshikawa, K
中科院分区：
文献类型：
--
作者：
Araki, S;Nakai, T;Yoshikawa, K
人们普遍认为，线性聚合物比相应的圆形聚合物更大，例如在端到端距离和回转半径方面。我们使用荧光显微镜测量了单个线性和环状 106-kbp DNA 分子的布朗运动。出乎意料的是，线性DNA的流体动力学半径明显小于环状DNA。 (c) 2005 Elsevier B.V. 保留所有权利。
it is generally accepted that linear polymers are larger, such as with regard to the end-to-end distance and gyration radius, than the corresponding circular polymers. We measured the Brownian motion of individual linear and circular 106-kbp DNA molecules using fluorescence microscopy. Unexpectedly, the hydrodynamic radius of linear DNA was markedly smaller than that of circular DNA. (c) 2005 Elsevier B.V. All rights reserved.