RELATIONSHIP OF CEREBRAL INTRAVENTRICULAR HEMORRHAGE AND EARLY-CHILDHOOD NEUROLOGIC HANDICAPS

RELATIONSHIP OF CEREBRAL INTRAVENTRICULAR HEMORRHAGE AND EARLY-CHILDHOOD NEUROLOGIC HANDICAPS
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DOI:
10.1016/s0022-3476(83)80366-7
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发表时间:
1983-01-01
影响因子:
5.1
通讯作者:
SCHAEFER, A
SCHAEFER, A
中科院分区:
医学2区
文献类型:
--
作者:
PAPILE, LA;MUNSICKBRUNO, G;SCHAEFER, A

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比较198例存活的极低出生体重儿(< 1501 gm)伴或不伴脑室内出血(CVH)的结局,以确定CVH是否与儿童早期发育或神经运动障碍有关。在10%的无CVH婴儿和28%的CVH婴儿中发现了重大障碍。在患有CVH的婴儿中,9%的1级CVH、11%的2级CVH、36%的3级CVH和76%的4级CVH存在严重障碍。出血后脑积水婴儿的主要残疾发生率(59%)与无脑积水婴儿(57%)相同。显然,1级和2级CVH不会增加婴儿的主要障碍的风险,3级和4级CVH与主要障碍有直接关系。
The outcome in 198 surviving very-low-birth-weight (< 1501 gm) infants with and without cerebral intraventricular hemorrhage (CVH) was compared to determine whether CVH is associated with early childhood developmental or neuromotor handicaps. Major handicaps were noted in 10% of the infants without and 28% of the infants with CVH. Among the infants with CVH, a major handicap was present in 9% with grade 1, 11% with grade 2, 36% with grade 3 and 76% with grade 4 CVH. Infants with posthemorrhagic hydrocephalus had the same incidence of major handicaps (59%) as did comparable infants with no hydrocephalus (57%). Evidently, grades 1 and 2 CVH do not increase an infant''s risk for major handicaps, and there is a direct relationship of grades 3 and 4 CVH and major handicaps.