Preparation and Characterization of Porous Electrochemical Sensor and Its Application in Voltammetric Determination of Paracetamol
Preparation and Characterization of Porous Electrochemical Sensor and Its Application in Voltammetric Determination of Paracetamol
复制标题
多孔电化学传感器的制备、表征及其在伏安法测定扑热息痛中的应用
DOI：
10.1166/sl.2011.1449
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发表时间：
2011-02
期刊：
影响因子：
--
通讯作者：
Nongyue He, et al
中科院分区：
文献类型：
--
作者：
Nongyue He, et al
基于多孔准碳糊电极（PPCPE）研制了一种新型的扑热息痛电化学传感器。详细讨论了PPCPE的物理化学性质，结果表明，PPCPE的比表面积为59.26 m2 · g-1，孔径为2 ~ 5 μm。所得PPCPE具有良好的亲水性。与聚吡咯修饰碳糊电极（PCPE）、碳纳米管修饰碳糊电极（CNTPE）和碳糊电极（CPE）相比，PPCPE对扑热息痛具有更高的选择性和灵敏度。在PPCPE处观察到的对乙酰氨基酚氧化与对乙酰氨基酚浓度的微分脉冲伏安图（DPV）峰电流校准曲线显示两个线性区域。第一个区域在2至0.1 mM的浓度范围内呈线性，相关系数为0.99638，对乙酰氨基酚浓度的线性区域为0.1至0.02 mM，相关系数为0.99818，检测限低至0.005mM，易于长期保存，重复使用性和稳定性好。
A novel and sensitive electrochemical sensor based on porous pseudo-carbon paste electrode (PPCPE) for paracetamol detection is described. The physical and chemical properties of PPCPE are discussed in detail, the results show that the specific surface area of PPCPE with pores ranging from 2 to 5 μm in diameter is 59.26 m2 · g–1. The obtained PPCPE possesses excellent hydrophilic. It was demonstrated that PPCPE exhibites a high selectivity and sensitivity toward paracetamol in comparison with polypyrrole modified carbon paste electrode (PCPE), carbon nanotube modified carbon paste electrode (CNTPE) and carbon paste electrode (CPE). The calibration curve for the differential pulse voltammogram (DPV) peak current observed for paracetamol oxidation versus paracetamol concentration at PPCPE shows two linear regions. The first region demonstrates linearity over a concentration range of 2 to 0.1 mM with a correlation coefficient of 0.99638, the linear region with the concentration of paracetamol is from 0.1 to 0.02 mM with a correlation coefficient of 0.99818, the detection limit is as low as 0.005 mM and the electrochemical sensor is easy to preserve for a long time and has good reusability and stability.