Palladium-catalyzed regio- and stereoselective cross-coupling of Baylis-Hillman adducts and bimetals: A novel method for the synthesis of substituted allylsilanes and allylgermanes
Palladium-catalyzed regio- and stereoselective cross-coupling of Baylis-Hillman adducts and bimetals: A novel method for the synthesis of substituted allylsilanes and allylgermanes
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DOI：
10.1021/om0492451
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发表时间：
2005-02-14
期刊：
影响因子：
2.8
通讯作者：
Dong, G
中科院分区：
文献类型：
--
作者：
Kabalka, GW;Venkataiah, B;Dong, G
本文报道了无膦钯配合物催化的Baylis-Hillman乙酸酯加合物与硅、锗试剂的交叉偶联反应。以高产率分离出3-取代-2-羰基烯丙基硅烷和烯丙基锗烷。交叉偶联反应具有区域和立体选择性。
Cross-coupling reactions between Baylis-Hillman acetate adducts and bimetallic reagents (Si-Si, Ge-Ge) catalyzed by a phosphine-free palladium complex are described. 3-Substituted-2-carbonylallylsilanes and allylgermanes were isolated in high yields. The cross-coupling reactions are regio- and stereoselective.