A unified mechanism for innate and learned visual landmark guidance in the insect central complex.
A unified mechanism for innate and learned visual landmark guidance in the insect central complex.
复制标题
昆虫中枢复合体中先天和后天视觉标志引导的统一机制。
DOI：
10.1371/journal.pcbi.1009383
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发表时间：
2021-09
影响因子：
4.3
通讯作者：
Webb B
中科院分区：
文献类型：
--
作者：
Goulard R;Buehlmann C;Niven JE;Graham P;Webb B
昆虫可以在新的和熟悉的环境中有效地导航，这需要它们如何被感官线索引导的灵活性。例如，一个突出的地标可以引发强烈的先天行为（吸引或趋性），但也可以在学习后作为导航记忆的一部分作为特定的方向线索。然而，允许这两种途径共存，相互作用或相互覆盖的机制在很大程度上是未知的。在这里，我们提出了一个模型的先天性和学习的指导的基础上的神经解剖学的中央复合体（CX），适应于控制地标指导行为的行为整合。我们认为奖励信号提供的先天吸引力的地标或长期的视觉记忆中的蘑菇体（MB），调制形成的本地矢量记忆的CX。使用操作性策略的模拟代理探索一个简单的世界，包含一个单一的视觉线索，我们展示了如何生成的短期记忆可以支持先天和学习的转向行为。此外，我们展示了这种架构是如何与观察到的影响，单方面MB病变的蚂蚁，导致先天行为的逆转是一致的。我们认为，在CX的方向记忆的形成可以被解释为转换奖励（积极或消极）的感官信号到一个映射的环境，描述的几何吸引力（或排斥）。我们讨论了如何这个计划可能代表一个理想的方式来结合联合收割机多感官信息收集在探索的环境，并支持最佳的线索整合。在本文中，我们模拟了神经通路，允许昆虫使用其内部指南针执行地标指导行为。首先，通过复制内部罗盘神经元和果蝇大脑中的转向神经元之间的神经连接的可用细节，我们表明该电路可以产生针对视觉地标的定向行为。然后，我们提出了一种机制，通过这种连接可以适应通过经验，以支持灵活的地标指导行为，如吸引力或menotaxis，即在任意方向上的运动相对于地标。这种机制允许一个简单的好/坏信号，从先天或长期记忆通路，被转换成一个定向的转向信号相对于视觉环境。此外，通过模拟木蚁蘑菇体中的病变实验，我们强调了模型与生物学观察的一致性。
Insects can navigate efficiently in both novel and familiar environments, and this requires flexiblity in how they are guided by sensory cues. A prominent landmark, for example, can elicit strong innate behaviours (attraction or menotaxis) but can also be used, after learning, as a specific directional cue as part of a navigation memory. However, the mechanisms that allow both pathways to co-exist, interact or override each other are largely unknown. Here we propose a model for the behavioural integration of innate and learned guidance based on the neuroanatomy of the central complex (CX), adapted to control landmark guided behaviours. We consider a reward signal provided either by an innate attraction to landmarks or a long-term visual memory in the mushroom bodies (MB) that modulates the formation of a local vector memory in the CX. Using an operant strategy for a simulated agent exploring a simple world containing a single visual cue, we show how the generated short-term memory can support both innate and learned steering behaviour. In addition, we show how this architecture is consistent with the observed effects of unilateral MB lesions in ants that cause a reversion to innate behaviour. We suggest the formation of a directional memory in the CX can be interpreted as transforming rewarding (positive or negative) sensory signals into a mapping of the environment that describes the geometrical attractiveness (or repulsion). We discuss how this scheme might represent an ideal way to combine multisensory information gathered during the exploration of an environment and support optimal cue integration. In this paper, we modeled the neural pathway allowing insects to perform landmark guided behaviours using their internal compass. First, by copying available details of the neural connectivity between internal compass neurons and steering neurons in the fruit-fly brain, we show this circuit can produce directed behaviour towards a visual landmark. We then propose a mechanism by which this connectivity could be adapted through experience to support flexible landmark guidance behaviours such as attraction or menotaxis, that is, movement in arbitrary directions relative to the landmark. This mechanism allows a simple goodness/badness signal, from innate or long-term memory pathways, to be converted into an oriented steering signal relative to the visual surroundings. Furthermore, by simulating lesion experiments in the mushroom bodies of wood ants we highlight the consistency of the model with biological observations.
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影响因子：
5.8
作者：
Gorostiza EA;Colomb J;Brembs B
通讯作者：
Brembs B
影响因子：
2.8
作者：
Franzke, Myriam;Kraus, Christian;el Jundi, Basil
通讯作者：
el Jundi, Basil
影响因子：
2.8
作者：
Endlein, Thomas;Sitti, Metin
通讯作者：
Sitti, Metin
影响因子：
64.8
作者：
Fisher YE;Lu J;D'Alessandro I;Wilson RI
通讯作者：
Wilson RI
DOI：
10.1016/j.cub.2009.06.022
发表时间：
2009-08-11
期刊：
Current biology : CB
影响因子：
--
作者：
Duistermars BJ;Chow DM;Frye MA
通讯作者：
Frye MA