Partial oxidation of TiN coating by hydrothermal treatment and ozone treatment to improve its osteoconductivity
Partial oxidation of TiN coating by hydrothermal treatment and ozone treatment to improve its osteoconductivity
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DOI：
10.1016/j.msec.2015.10.024
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发表时间：
2016-02-01
影响因子：
7.9
通讯作者：
Ishikawa, Kunio
中科院分区：
文献类型：
--
作者：
Shi, Xingling;Xu, Lingli;Ishikawa, Kunio
纯钛制成的牙科植入物在日常口腔卫生程序中会受到磨损和刮伤。这会导致不可逆的表面损伤，促进细菌粘附并增加种植体周围炎的风险。为了克服这些问题，引入氮化钛（TiN）涂层来提高纯钛的表面硬度。然而，TiN的骨传导性被认为与钛及其合金相似或上级，因此表面改性是必要的。为了提高TiN涂层的骨传导性，采用水热氧化和臭氧氧化两种方法对气体氮化法制备的TiN涂层进行了部分氧化处理。研究了FIT处理和O-3处理对TiN表面性质的影响，并使用成骨细胞评价评估了处理后的体外骨传导性。结果表明，热处理的临界温度为100 ℃，因为较高的温度会损害TiN涂层的硬度。相比之下，O-3处理更有效地氧化TiN表面，改善其润湿性，同时保持其形态和硬度。与未处理的标本相比，氧化标本，尤其是O-3处理的标本，成骨细胞的附着，增殖，碱性磷酸酶（ALP）的表达和矿化得到改善。这些效果似乎是部分氧化的结果，以及改善的亲水性和表面去污。最后得出结论，部分氧化TiN是一种很有前途的用于牙科种植体的涂层。(C)2015爱思唯尔B. V.保留所有权利。
Dental implants made of pure titanium suffer from abrasion and scratch during routine oral hygiene procedures. This results in an irreversible surface damage, facilitates bacteria adhesion and increases risk of peri-implantitis. To overcome these problems, titanium nitride (TIN) coating was introduced to increase surface hardness of pure titanium. However, the osteoconductiyity of TiN is considered to be similar or superior to that of titanium and its alloys and therefore surface modification is necessary. In this study, TIN coating prepared through gas nitriding was partially oxidized by hydrothermal (HT) treatment and ozone (O-3) treatment in pure water to improve its osteoconductivity. The effects of FIT treatment and O-3 treatment on surface properties of TiN were investigated and the osteoconductivity after undergoing treatment was assessed in vitro using osteoblast evaluation. The results showed that the critical temperature for HT treatment was 100 degrees C since higher temperatures would impair the hardness of TIN coating. By contrast, O-3 treatment was more effective in oxidizing TiN surfaces, improving its wettability while preserving its morphology and hardness. Osteoblast attachment, proliferation, alkaline phosphatase (ALP) expression and mineralization were improved on oxidized specimens, especially on O-3 treated specimens, compared with untreated ones. These effects seemed to be consequences of partial oxidation, as well as improved hydrophilicity and surface decontamination. Finally, it was concluded that, partially oxidized TiN is a promising coating to be used for dental implant. (C) 2015 Elsevier B.V. All rights reserved.