Development of the human fetal auditory cortex: growth of afferent fibres.
Development of the human fetal auditory cortex: growth of afferent fibres.
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人类胎儿听觉皮层的发育：传入纤维的生长。
DOI：
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发表时间：
1983
期刊：
影响因子：
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通讯作者：
L. Mrzljak
中科院分区：
文献类型：
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作者：
J. Krmpotić‐Nemanić;I. Kostović;Z. Kelović;D. Nemanić;L. Mrzljak
用乙酰胆碱酯酶(AChE；EC 3.1.1.7)组织化学方法，对10~28周胎儿大脑皮质下纤维的连续发育和生长进行了研究。研究发现，接近胎儿听觉皮质的丘脑和基底端脑纤维在长时间的生长过程中具有很强的AChE反应。在最小的胎儿(10.5周)，可以看到一个突出的纤维系统从丘脑腹后区出现，而听觉新大脑皮质没有AChE染色。在年龄较大的胎儿(16-18周)，起源于丘脑腹后部和基底端脑的AChE阳性纤维穿透听觉皮质的‘亚板层’。根据“亚板层”的AChE反应性，可以从周围的新皮质区域中辨认出听觉皮质。在年龄最大的胎儿(22-28周)，丘脑来源的AChE阳性纤维穿透发育中的听觉皮质的皮质板。
The sequential development and growth of the subcortico-cortical fibres have been studied by means of acetylcholinesterase (AChE; acetylcholine acetylhydrolase; EC 3.1.1.7) histochemistry on the serial sections obtained from brains of human fetuses ranging from 10 to 28 weeks of gestation. It was found that thalamic and basal telencephalic fibres approaching the fetal auditory cortex have very strong AChE reactivity during a prolonged period of growth. In the youngest fetuses (10.5 weeks) a prominent fibre system was seen emerging from the ventroposterior thalamic territory while the auditory neopallium was free of AChE staining. In older fetuses (16-18 weeks) AChE-positive fibres originating in the ventroposterior thalamus and basal telencephalon penetrate the 'subplate layer' of the auditory cortex. On the basis of AChE reactivity of the 'subplate layer' the auditory cortex can be delineated from the surrounding neocortical areas. In the oldest fetuses (22-28 weeks) AChE-positive fibres of thalamic origin penetrate the developing cortical plate of the auditory cortex.