Testing for nonlinearity in functional near-infrared spectroscopy of brain activities by surrogate data methods

Testing for nonlinearity in functional near-infrared spectroscopy of brain activities by surrogate data methods
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DOI:
10.2170/physiolsci.rp012707
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发表时间:
2008-02-01
影响因子:
2.3
通讯作者:
Nakagawa, Masahiro
Nakagawa, Masahiro
中科院分区:
医学4区
文献类型:
--
作者:
Khoa, Truong Q. D.;Thang, Hoang M.;Nakagawa, Masahiro

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现代物理学方法对生物医学研究越来越重要。由于各种各样的原因,生物医学和现代物理学方法之间存在着差距。在这项工作中,替代数据的技术已被用来作为一种方法来测试的线性或非线性的生物医学功能近红外光谱(fNIRS)信号观察大脑活动。通过三阶自协方差、时间反转引起的不对称性和延迟向量方差三种不同的替代检验,脑活动对fNIRS生物医学信号的动态响应很可能是一个非线性系统。
Methods of contemporary physics are increasingly important for biomedical research. For a multitude of diverse reasons there exists a gap between the practitioners of biomedicine and modern physics methodologies. In this work, the technique of surrogate data has been used as a method to test for the linearity or nonlinearity of biomedical functional near-infrared spectroscopy (fNIRS) signals observing brain activities. Throughout three different surrogate tests, the third-order auto-covariance, the asymmetry resulting from time reversal, and the delay vector variance, the dynamic response of brain activities through fNIRS biomedical signals is very likely to be a nonlinear system.