Driver route-following and safety errors in early Alzheimer disease
Driver route-following and safety errors in early Alzheimer disease
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DOI：
10.1212/01.wnl.0000139301.01177.35
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发表时间：
2004-09-14
期刊：
影响因子：
9.9
通讯作者：
Dawson, JD
中科院分区：
文献类型：
--
作者：
Uc, EY;Rizzo, M;Dawson, JD
目的：评估患有阿尔茨海默病 (AD) 的驾驶员在执行路线跟踪任务时的导航和安全错误。设计/方法：对 32 名可能患有轻度 AD（根据国家神经和交流障碍研究所标准）的受试者和 136 名神经功能正常的老年人进行了一系列对安全汽车驾驶至关重要的视觉和认知能力测试。每位驾驶员还使用仪表车辆执行在道路上管理的路线查找任务。主要结果变量是 1) 错误转弯的次数； 2）损失次数； 3）有故障的安全错误。结果：轻度 AD 驾驶员尽管基本车辆控制能力正常，但与对照受试者相比，转弯不正确、迷路的频率和过失安全错误的频率明显更高。导航和安全错误是通过对早期 AD 视觉和认知能力下降敏感的标准化测试的分数来预测的。结论：患有阿尔茨海默病的驾驶员在执行对驾驶员记忆、注意力和感知能力有要求的路线跟踪任务时比神经正常的驾驶员犯更多错误。遵循路线指示的要求可能会增加驾驶过程中的认知负荷，这可能解释了安全错误数量增加的原因。
Objective: To assess navigation and safety errors during a route-following task in drivers with Alzheimer disease (AD). Design/Methods: Thirty-two subjects with probable AD ( by National Institute of Neurological and Communicative Disorders criteria) of mild severity and 136 neurologically normal older adults were tested on a battery of visual and cognitive tests of abilities that are critical to safe automobile driving. Each driver also performed a route-finding task administered on the road in an instrumented vehicle. Main outcome variables were number of 1) incorrect turns; 2) times lost; and 3) at-fault safety errors. Results: The drivers with mild AD made significantly more incorrect turns, got lost more often, and made more at-fault safety errors than control subjects, although their basic vehicular control abilities were normal. The navigational and safety errors were predicted using scores on standardized tests sensitive to visual and cognitive decline in early AD. Conclusions: Drivers with Alzheimer disease made more errors than neurologically normal drivers on a route-following task that placed demands on driver memory, attention, and perception. The demands of following route directions probably increased the cognitive load during driving, which might explain the higher number of safety errors.