Influenza vaccination hesitancy and its determinants among elderly in China: A national cross-sectional study
Influenza vaccination hesitancy and its determinants among elderly in China: A national cross-sectional study
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DOI：
10.1016/j.vaccine.2022.06.063
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发表时间：
2022-08-10
期刊：
影响因子：
5.5
通讯作者：
Fang, Hai
中科院分区：
文献类型：
--
作者：
Hou, Zhiyuan;Guo, Jia;Fang, Hai
背景：我国老年人由于疫苗接种率低，面临着季节性流感的严重威胁。本研究旨在探讨中国老年人流感疫苗接种犹豫的患病率和影响因素。方法：2019年，在中国10个省份招募了3849名老年人进行横断面调查。结果：37.18%的老年人对流感疫苗接种有不同程度的犹豫，19.28%的老年人犹豫，17.90%的老年人拒绝接种流感疫苗，其中19.28%的老年人持怀疑态度，17.90%的老年人拒绝接种。只有39.10%的受访者认为自己是流感疫苗接种的优先群体，13.93%的受访者表示收到医护人员的疫苗接种建议。受教育程度较高和来自城市地区的受访者的疫苗犹豫几率明显高于他们的同行。对疫苗安全性的信心与对疫苗的犹豫有负相关，但对疫苗有效性的信心没有这种关联。认为自己极易感染流感的受访者（AOR = 0.85; 95% CI = 0.77-0.93）和那些知道老年人是流感疫苗接种的优先群体的人（AOR = 0.51; 95% CI = 0.41-0.64）有明显较低的几率成为拒绝者。本研究发现，中国老年人，尤其是受过良好教育和居住在城市的受访者，对流感疫苗接种犹豫不决的患病率很高。政府应通过文化上适当的沟通、疫苗接种补贴和通过初级保健专业人员积极推广疫苗来解决疫苗犹豫问题。(c)2022由Elsevier Ltd.出版
Background: The Chinese elderly face a significant threat from seasonal influenza, owing to the consis-tently low vaccination coverage. This study investigated the prevalence and determinants of influenza vaccination hesitancy among the Chinese elderly.Methods: In 2019, 3849 elderly individuals from 10 provinces in China were recruited in a cross-sectional survey. Multinomial logistic regression was applied to investigate the determinants of influenza vaccina-tion hesitancy.Results: Among the elderly respondents, 37.18% expressed some degree of hesitancy towards influenza vaccination: 19.28% were hesitant, and 17.90% refused influenza vaccination, including 19.28% acceptors with doubts and 17.90% refusers. Only 39.10% of the respondents considered themselves as the priority group for influenza vaccination, and 13.93% reported receiving a recommendation for vaccination from healthcare workers. Respondents with higher education levels and from urban areas had significantly higher odds of vaccine hesitancy than their counterparts. Confidence in the safety of vaccines was neg-atively associated with vaccine hesitancy, but confidence in vaccine efficacy had no such association. Respondents who perceived themselves as highly susceptible to influenza (AOR = 0.85; 95 %CI = 0.77-0.93) and those aware of the elderly as a priority group for influenza vaccination (AOR = 0.51; 95 %CI = 0.41-0.64) had a significantly lower odds of being refusers.Conclusion: This study found a high prevalence of hesitancy towards influenza vaccination among the Chinese elderly, especially well-educated and urban-dwelling respondents. The government should address vaccine hesitancy through culturally appropriate communication, subsidies for vaccination, and actively promoting vaccines through primary care professionals. (c) 2022 Published by Elsevier Ltd.