Microarray technology applied to the complex disorder of preeclampsia

Microarray technology applied to the complex disorder of preeclampsia
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DOI:
10.1111/j.1552-6909.2008.00232.x
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发表时间:
2008-03-01
影响因子:
1.8
通讯作者:
Conley, Yvette P.
Conley, Yvette P.
中科院分区:
医学4区
文献类型:
--
作者:
Founds, Sandra A.;Dorman, Janice S.;Conley, Yvette P.

文献摘要

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先兆子痫是一种病因不明的危及生命的围产期并发症。微阵列技术已经表征了复杂疾病如先兆子痫中的全局基因表达。护理研究和未来的实践可能会结合微阵列分析的结果,以确定易感性和预防疾病,设计和监测个性化治疗。微阵列技术的概述,重点是它如何能够告知先兆子痫的基因组学,可能会提供概念,以改善未来的母婴护理。
Preeclampsia is a life-threatening perinatal complication with unknown etiology. Microarray technology has characterized global gene expression in complex disorders such as preeclampsia. Nursing research and future practice may incorporate findings from microarray analyses to identify susceptibility to and prevent disease, to design and monitor personalized therapies. This overview of microarray technology, with emphasis on how it can inform genomics of preeclampsia, may provide concepts to improve future maternal-neonatal nursing care.