Draft Genome Sequence of the Marine Streptomyces sp Strain PP-C42, Isolated from the Baltic Sea
Draft Genome Sequence of the Marine Streptomyces sp Strain PP-C42, Isolated from the Baltic Sea
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DOI：
10.1128/jb.05097-11
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发表时间：
2011-07-01
影响因子：
3.2
通讯作者：
Cai, Daguang
中科院分区：
文献类型：
--
作者：
Fan, Longjiang;Liu, Yun;Cai, Daguang
链霉菌是需氧革兰氏阳性菌的一个分支，是放线菌中最大的属。链霉菌的特点是复杂的次级代谢，产生当今临床使用的天然抗生素的三分之二以上。在这里，我们报告了从海洋环境中分离出的链霉菌菌株 PP-C42 的基因组序列草案。可以从基因组中鉴定出多种次级代谢物以及抗菌肽的独特基因和基因簇的子集，这显示出作为新型生物活性化合物来源的巨大前景。
Streptomyces, a branch of aerobic Gram-positive bacteria, represents the largest genus of actinobacteria. The streptomycetes are characterized by a complex secondary metabolism and produce over two-thirds of the clinically used natural antibiotics today. Here we report the draft genome sequence of a Streptomyces strain, PP-C42, isolated from the marine environment. A subset of unique genes and gene clusters for diverse secondary metabolites as well as antimicrobial peptides could be identified from the genome, showing great promise as a source for novel bioactive compounds.