Leakage evaluation of root end filling materials using endotoxin
Leakage evaluation of root end filling materials using endotoxin
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DOI：
10.1097/00004770-200201000-00002
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发表时间：
2002-01-01
影响因子：
4.2
通讯作者：
Kettering, JD
中科院分区：
文献类型：
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作者：
Tang, HM;Torabinejad, M;Kettering, JD
矿物三氧化物聚集体（MTA）已被证明具有优异的密封能力时，测试与染料，细菌，和流体过滤技术。内毒素是革兰氏阴性菌细胞壁的一种成分，已被认为在神经根周围病变的发病机制中发挥作用。本研究使用改良的鲎变形细胞溶解物试验检测是否存在内毒素作为示踪剂，并比较了Super-EBA、骨水泥、汞合金和MTA的密封能力。结果表明，MTA组在1、2、6、12 wk时内毒素漏出量明显低于对照组和银汞合金组（p < 0.05），在2、12 wk时内毒素漏出量明显低于Super-EBA组（p < 0.05）。
Mineral trioxide aggregate (MTA) has been shown to possess excellent sealing ability when tested with dye, bacteria, and a fluid filtration technique. Endotoxin, a component of the cell wall of Gram-negative bacteria, has been proposed to play a role in the pathogenesis of periradicular lesions. This study used a modified Limulus Amebocyte Lysate test for the presence of endotoxin as a tracer and compared the sealing ability of Super-EBA, IRM, amalgam, and MTA. The results showed that MTA permitted less endotoxin leakage than IRM and amalgam at 1, 2,6, and 12 wk (p < 0.05), and leaked less than Super-EBA at 2 and 12 wk (p < 0.05).