Predictors of functional level and quality of life at 6 months after a first-ever stroke: the KOSCO study
Predictors of functional level and quality of life at 6 months after a first-ever stroke: the KOSCO study
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DOI：
10.1007/s00415-016-8119-y
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发表时间：
2016-06-01
影响因子：
6
通讯作者：
Kim, Yun-Hee
中科院分区：
文献类型：
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作者：
Chang, Won Hyuk;Sohn, Min Kyun;Kim, Yun-Hee
预测功能结局和生活质量（QOL）对卒中患者的治疗至关重要。本研究的目的是分析影响首次脑卒中患者6个月后功能状态和生活质量的因素。本研究是韩国卒中队列功能和康复研究的中期分析，旨在纳入首次卒中患者的10年随访。本研究分析了2857例患者的数据，这些患者在卒中发作后6个月时完成了功能独立性测量（ESTA）和欧洲生活质量-5D（EQ-5D）的面对面评估。使用多变量回归分析来分析可能影响中风后6个月FIM和EQ-5D结果的因素。在本研究的患者中，80.1%患有缺血性卒中，19.9%患有出血性卒中。脑卒中后6个月时，功能独立性的独立预测因素包括年龄、初始卒中严重程度、住院时间和出院时运动、上肢和语言功能水平。对于卒中后6个月时通过EQ-5D测量的QOL，年龄、住院时间和出院时的运动功能是显著的预测因素。总之，适当的治疗，以实现最大的功能增益在出院时可能是一个重要的因素，在改善功能独立性和生活质量的慢性阶段中风幸存者。这些结果提供了有用的信息，建立全面和系统的照顾中风病人。
Predicting functional outcome and quality of life (QOL) is critical to the treatment of patients with stroke. The purpose of this study was to analyze the factors influencing functional status and QOL of stroke patients 6 months after a first-ever stroke. This study was an interim analysis of the Korean Stroke Cohort for Functioning and Rehabilitation Study, designed to include 10 years of follow-up for first-ever stroke patients. This study analyzed data from 2857 patients who completed face-to-face assessments with the functional independence measurement (FIM) and Euro Quality of Life-5D (EQ-5D) at 6 months after stroke onset. A multivariate regression analysis was used to analyze factors that potentially influenced FIM and EQ-5D results at 6 months after stroke. Of the patients in this study, 80.1 % suffered from ischemic stroke and 19.9 % experienced hemorrhagic stroke. The independent predictors of functional independency measured by FIM at 6 months after stroke were age, initial stroke severity, duration of hospitalization, and functional level at discharge in terms of motor, ambulation, and language. For QOL measured by EQ-5D at 6 months after stroke, age, duration of hospitalization, and motor function at discharge were significant predictors. In conclusion, proper treatment to achieve maximal functional gain at discharge may be an important factor in improving functional independency and QOL in chronic stage stroke survivors. These results provide useful information for establishing comprehensive and systematic care for stroke patients.