Area 18 corticotectal cells: response properties and identification of sustaining geniculate inputs.
Area 18 corticotectal cells: response properties and identification of sustaining geniculate inputs.
复制标题
区域 18 皮质顶盖细胞：响应特性和维持膝状体输入的识别。
DOI：
10.1152/jn.1991.65.5.1078
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发表时间：
1991
影响因子：
2.5
通讯作者：
Lee,C
中科院分区：
文献类型：
--
作者：
Weyand,TG;Malpeli,JG;Lee,C
1.我们研究了反应特性和膝状体输入的35个逆向识别皮质顶盖（CT）细胞内的区域18瘫痪，麻醉猫。23个是标准的复杂或hypercomplex，11个是特殊的复杂，1个是简单的。2.在区域18中的CT细胞的响应特性一般是非常相似的区域17 CT细胞，包括标准和特殊复杂的CT细胞，几乎相同的长度响应函数，和类似的方向和方向调谐的比例相似的先前的研究中所检查的。3. 18区的CT细胞正在快速传导。它们比17区CT细胞快得多。4.我们研究了丘脑输入CT细胞的成分，通过注射氯化钴可逆地灭活背外侧膝状体核的A层和/或C层的一部分。阻断层A强烈减弱了约一半测试细胞的视觉反应。单独阻断C层通常仅具有中等影响，但同时阻断A层和C层证明了许多细胞的大量C层输入。与CT细胞类别和对A层的依赖性之间存在强相关性的区域17不同，没有单个感受场参数或参数集与对A层的依赖性相关。然而，细胞受影响最小的同时封锁层A和C层是特别复杂的，这表明，在17区，18区特殊复杂的CT细胞集成更多的膝状体输入比标准复杂的CT细胞。5.我们建议，区域17和区域18 CT细胞的响应特性的相似性，结果从他们的参与类似的层间柱状电路和膝状体控制的模式的差异反映了膝状体输入到这两个领域的全球模式的差异。
1. We examined the response properties and geniculate inputs of 35 antidromically identified corticotectal (CT) cells within area 18 of the paralyzed, anesthetized cat. Twenty-three were either standard complex or hypercomplex, 11 were special complex, and 1 was simple. 2. The response properties of CT cells in area 18 were in general quite similar to those examined in a previous study of area 17 CT cells, including similar proportions of standard and special complex CT cells, virtually identical length-response functions, and similar orientation and direction tuning. 3. Area 18 CT cells are rapidly conducting. They are considerably faster than area 17 CT cells. 4. We investigated the composition of thalamic inputs to CT cells by reversibly inactivating a portion of layer A and/or the C layers of the dorsal lateral geniculate nucleus with injections of cobaltous chloride. Blocking layer A strongly attenuated the visual responsiveness of about half of the cells tested. Blocking the C layers alone generally had only moderate effects, but simultaneous blockade of layer A and the C layers demonstrated a substantial C-layer input to many cells. Unlike area 17 in which there is a strong correlation between CT cell class and dependence on layer A, no single receptive-field parameter nor set of parameters was correlated with dependence on layer A. However, cells least affected by simultaneous blockade of layer A and the C layers were special complex, suggesting that, as in area 17, area 18 special complex CT cells integrate more geniculate inputs than standard complex CT cells. 5. We propose that the similarities of response properties of area 17 and area 18 CT cells results from their participation in similar interlaminar columnar circuits and that differences in the patterns of geniculate control reflect differences in the global patterns of geniculate inputs to these two areas.