Schizotypy and psychosis-like experiences from recreational cannabis in a non-clinical sample
Schizotypy and psychosis-like experiences from recreational cannabis in a non-clinical sample
复制标题
DOI：
10.1017/s0033291707002619
复制
发表时间：
2008-09-01
影响因子：
6.9
通讯作者：
Lewis, S.
中科院分区：
文献类型：
--
作者：
Barkus, E.;Lewis, S.
背景大麻使用和精神病之间的关系仍然是一个有争议的问题。在一般人群中对娱乐性大麻使用的主观体验的个体差异可能对大麻和精神病症状之间的病因学关系提供一些线索。我们假设，大麻使用后的主观经验，但不是在使用模式的个体差异，将解释automotypy。在至少使用过一次大麻的532名年轻人的样本中，我们研究了大麻体验问卷（CEQ）和分裂型人格问卷（SPQ）之间的关系。此外，我们还研究了CEQ.Results.的心理测量学特性。我们重复了我们以前报告的发现，即精神分裂症与增加的精神病样经历和后遗症有关，但也发现高分的精神分裂症患者在吸食大麻时报告了更愉快的经历。使用新的分量表来自主成分分析（PCA），我们发现，精神病样的项目是最相关的，无论是在大麻的立即使用和大麻使用的后效的不同比率的automotypy。使用大麻的高得分的精神病类型在使用期间和使用后经历了更多的精神病样症状。我们的研究结果表明，大麻的使用可能揭示了那些具有高相似性特征的人对精神病的潜在脆弱性。
Background. The relationship between cannabis use and psychosis is still a matter for debate. Accounting for the individual differences in subjective experiences to recreational cannabis use in the general population may hold some clues to the aetiological relationship between cannabis and psychotic symptoms. We hypothesized that schizotypy would account for the individual differences in subjective experiences after cannabis use but not in patterns of use.Method. In a sample of 532 young people who had used cannabis at least once, we examined the relationship between the Cannabis Experiences Questionnaire (CEQ) and the Schizotypal Personality Questionnaire (SPQ). Additionally, we examined the psychometric properties of the CEQ.Results. We replicated our previously reported findings that schizotypy was associated with increased psychosis-like experiences and after-effects, but also found that high-scoring schizotypes reported more pleasurable experiences when smoking cannabis. Using new subscales derived from principal components analysis (PCA), we found that the psychosis-like items were most related to varying rates of schizotypy both during the immediate use of cannabis and in the after-effects of cannabis use. High-scoring schizotypes who used cannabis experienced more psychosis-like symptoms during and after use.Conclusions. Our results suggest that cannabis use may reveal an underlying vulnerability to psychosis in those with high schizotypal traits.