Conversion of Sugars to Lactic Acid Derivatives Using Heterogeneous Zeotype Catalysts
Conversion of Sugars to Lactic Acid Derivatives Using Heterogeneous Zeotype Catalysts
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DOI：
10.1126/science.1183990
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发表时间：
2010-04-30
期刊：
影响因子：
56.9
通讯作者：
Taarning, Esben
中科院分区：
文献类型：
--
作者：
Holm, Martin Spangsberg;Saravanamurugan, Shunmugavel;Taarning, Esben
目前，很少有具有商业价值的化合物可以通过非发酵方法直接从碳水化合物中获得。我们在这里描述了由普通糖直接形成乳酸甲酯的催化过程。Lewis酸性型，如Sn-Beta，在160℃催化溶解在甲醇中的单糖和双糖转化为乳酸甲酯，以蔗糖为底物，乳酸甲酯收率可达68%，多相催化剂经过滤后易于回收，煅烧后可多次重复使用，产物选择性无明显变化。
Presently, very few compounds of commercial interest are directly accessible from carbohydrates by using nonfermentive approaches. We describe here a catalytic process for the direct formation of methyl lactate from common sugars. Lewis acidic zeotypes, such as Sn-Beta, catalyze the conversion of mono-and disaccharides that are dissolved in methanol to methyl lactate at 160 C. With sucrose as the substrate, methyl lactate yield reaches 68%, and the heterogeneous catalyst can be easily recovered by filtration and reused multiple times after calcination without any substantial change in the product selectivity.