One-Pot, Pd-Catalyzed Synthesis of trans-Dihydrobenzofurans from o-Aminophenols
One-Pot, Pd-Catalyzed Synthesis of trans-Dihydrobenzofurans from o-Aminophenols
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DOI：
10.1021/ol100433z
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发表时间：
2010-05-07
期刊：
影响因子：
5.2
通讯作者：
Sefkow, Michael
中科院分区：
文献类型：
--
作者：
Coy B, Ericsson D.;Jovanovic, Ljubisa;Sefkow, Michael
以邻氨基苯酚和苯基丙烯为原料，通过钯催化的非对映选择性氧化芳基化反应，一锅法合成了反式二氢苯并呋喃。介绍了该方法的发展和优化。
An efficient and facile synthesis of trans-dihydrobenzofurans has been accomplished from o-aminophenols and phenylpropenes via a novel (one-pot) diastereoselective Pd-catalyzed oxyarylation reaction. The development and optimization of this method is described.