Urodynamic study and quality of life in patients with fibromyalgia and lower urinary tract symptoms
Urodynamic study and quality of life in patients with fibromyalgia and lower urinary tract symptoms
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DOI：
10.1007/s00192-008-0577-z
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发表时间：
2008-08-01
影响因子：
1.8
通讯作者：
Batista Castello Girao, Manoel Joao
中科院分区：
文献类型：
--
作者：
de Araujo, Maita Poli;Faria, Alex Carvalho;Batista Castello Girao, Manoel Joao
本研究的目的是评估患有纤维肌痛 (FM) 和下尿路症状 (LUTS) 的女性的临床和尿动力学观察结果。 51 名 FM 和 LUTS 患者以及 50 名 LUTS 无 FM 患者回答了有关泌尿系统症状的问题以及两份有关生活质量测量的问卷：“医疗结果研究 36 项简短健康调查”和“King 健康问卷”。评估的尿动力学参数如下：最大膀胱测压能力、咳嗽引起的尿液流失、Valsalva漏点压力和逼尿肌过度活动（DO）。这些组在年龄、产次、体重指数和生殖器脱垂方面是同质的。 FM 组中尿频增加（p=0.007）和急迫性尿失禁（p=0.004）等症状在统计上更为常见。 DO 是 FM 患者中统计上最常见的尿动力学观察结果 (p=0.02)。关于生活质量的调查问卷，纤维肌痛和LUTS患者在所有领域的结果最差。总之，FM 和 LUTS 患者更频繁地出现逼尿肌过度活动以及尿频增加，导致生活质量恶化。
The aim of this study was to evaluate clinical and urodynamic observations on women with fibromyalgia (FM) and lower urinary tract symptoms (LUTS). Fifty-one patients with FM and LUTS and 50 patients with LUTS without FM answered questions about urinary symptoms and also two questionnaires about quality of life measures: "Medical Outcomes Study 36-Item Short-Form Health Survey" and "King's Health Questionnaire". The urodynamic parameters evaluated were the following: maximum cystometric capacity, urine loss due to cough, Valsalva leak point pressure, and detrusor overactivity (DO). The groups were homogeneous concerning age, parity, body mass index, and genital prolapse. Symptoms such as increase of urinary frequency (p=0.007) and urge urinary incontinence (p=0.004) were statistically more common in the FM group. DO was the statistically most common urodynamic observation in patients with FM (p=0.02). Regarding the questionnaires about quality of life, the patients with fibromyalgia and LUTS had the worst results in all fields. In conclusion, patients with FM and LUTS have detrusor overactivity more often as well as an increase of urinary frequency, contributing to the quality of life worsening.