Topoisomerases, chromatin and transcription termination
Topoisomerases, chromatin and transcription termination
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DOI：
10.4161/trns.2.2.14411
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发表时间：
2011-01-01
影响因子：
3.6
通讯作者：
Ekwall, Karl
中科院分区：
文献类型：
--
作者：
Durand-Dubief, Mickael;Svensson, J. Peter;Ekwall, Karl
In eukaryotes transcription is complicated by the DNA being packed in nucleosomes and by supercoils induced by opening of the DNA double helix during elongation. Here we discuss our recent genome-wide work regarding topoisomerases and their role in chromatin remodeling during the transcription cycle and we report a novel function for topoisomerases in transcription termination.
