Calcium Requirement for Melanophore-Stimulating Hormone Action on Melanophores
Calcium Requirement for Melanophore-Stimulating Hormone Action on Melanophores
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黑色素细胞刺激激素对黑色素细胞作用的钙需求
DOI：
10.1126/science.173.4000.923
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发表时间：
1971
期刊：
影响因子：
56.9
通讯作者：
M. Hadley
中科院分区：
文献类型：
--
作者：
D. Vesely;M. Hadley
体外，黑素细胞刺激激素对蜥蜴（Anolis carolinensis）黑素细胞内黑素体分散的作用特别需要钙离子。对这种激素的反应与 Ca2+ 离子的浓度直接相关。如果存在 Ca2+，锂、胆碱、铷和铯将取代林格溶液中的钠和钾。黑素体分散本身不需要钙离子，因为茶碱或二丁酰环腺苷单磷酸在没有钙的情况下可逆地使蜥蜴皮肤变黑。
The calcium ion is specifically required for the action of melanophorestimulating hormone on melanosome dispersion within lizard (Anolis carolinensis) melanophores in vitro. The response to this hormone is directly related to the concentration of the Ca2+ ion. Lithium, choline, rubidium, and cesium will replace the sodium and potassium of Ringer solution if Ca2+ is present. Calcium ions are not required for melanosome dispersion itself, since theophylline or dibutyryl cyclic adenosine monophosphate reversibly darkens lizard skins in the absence of calcium.