A fuzzy logic based closed-loop control system for blood glucose level regulation in diabetics
A fuzzy logic based closed-loop control system for blood glucose level regulation in diabetics
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DOI：
10.1080/03091900410001709088
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发表时间：
2005-03-01
影响因子：
--
通讯作者：
Masadeh, M. A.
中科院分区：
文献类型：
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作者：
Ibbini, M. S.;Masadeh, M. A.
在这项研究中，一个闭环系统，以控制血糖水平的糖尿病患者I型提出。该控制方案基于模糊逻辑控制理论，以维持4.5 mmol l（-1）的正常血糖平均值和严重初始状态下游离血浆胰岛素浓度的正常条件;特别是当糖尿病患者受到葡萄糖餐干扰或测量的葡萄糖水平由于测量仪器中的误差而波动时。所提出的控制器已被证明优于其他传统的控制疗法。虽然模糊逻辑控制器在许多领域都表现出良好的效果，比较研究与众所周知的传统控制器，如比例积分微分（PID）和连续胰岛素输注控制策略。仿真结果，所提出的控制器，提出和讨论。
In this study, a closed-loop system to control the plasma glucose level in patients with diabetes mellitus type I is proposed. This control scheme is based on fuzzy logic control theory to maintain a normoglycaemic average of 4.5 mmol l(-1) and the normal conditions for free plasma insulin concentration in severe initial state; in particular, when the diabetic patient is subjected to a glucose meal disturbance or fluctuations in the measured glucose level due to error in the measuring instrument. The proposed controller has demonstrated superiority over other conventional controlling therapies. While fuzzy logic controllers have shown promising results in many fields, a comparative study is presented with well-known conventional controllers such as Proportional-Integral-Derivative (PID) and continuous insulin infusion control strategies. The simulated results, for the proposed controller, are presented and discussed.