Strain imaging using speckle tracking in the cardiometabolic syndrome: method and utility.
Strain imaging using speckle tracking in the cardiometabolic syndrome: method and utility.
复制标题
在心脏代谢综合征中使用散斑跟踪进行应变成像：方法和实用性。
DOI：
10.1111/j.1559-4572.2008.00025.x
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发表时间：
2008
期刊：
影响因子：
--
通讯作者：
Peterson,LindaR
中科院分区：
文献类型：
--
作者：
StVrain,Jeanette;Bilhorn,Kyle;Kurup,Suraj;Peterson,LindaR
在过去的二十年中，肥胖和心血管代谢综合征（CMS）的发病率急剧上升。仅在美国，估计就有4200万人受到CMS的影响。除了糖尿病和高血压并发症外，这一人群还存在发生缺血性和非缺血性心力衰竭的风险。虽然肥胖和CMS的其他方面导致左室重构和舒张功能障碍是公认的，但关于CMS对收缩功能的影响确实存在争议。这部分是由于肥胖与血浆量增加有关。因此，任何与负荷相关的收缩功能测量，如心输出量，都必然受到容积和收缩性变化的影响。肥胖者左室收缩功能指标的不同索引方法也可能影响收缩功能结果。例如，心脏输出量可能在肥胖时增加，但当以体表面积为指标时，心脏指数可能较低。因此，更新、更独立于负荷的无创方法对于更好地表征左室收缩功能是必要的。
During the past twenty years, there has been a dramatic increase in obesity and the cardiometabolic syndrome (CMS). In the United States alone, there are an estimated 42 million persons affected by CMS. 1 In addition to complications from diabetes and hypertension, this population is at risk for the development of both ischemic and nonischemic heart failure. 2 Although it is fairly well accepted that obesity and other aspects of CMS contribute to left ventricular (LV) remodeling and diastolic dysfunction, controversy does exist as to the effects of CMS on systolic function. 2 This is partly due to the fact that obesity is associated with an increase in plasma volume. 2 Thus, any load-dependent measures of systolic function, eg, cardiac output, are necessarily affected by alterations in volume as well as contractility. Different methods for indexing LV systolic function measures in obese subjects may also affect systolic function results. For example, cardiac output may be increased in obesity but when indexed for body surface area, cardiac index may be low. Thus, newer, more load-independent noninvasive methods are necessary for better characterizing LV systolic function.